T Cell Recognition of CNS Autoantigens in Multiple Sclerosis and Neuromyelitis Optica
Multiple sclerosis (MS) and neuromyelitis optica (NMO) are believed to be autoimmune conditions in which the immune system (which normally helps fight infections) causes damage to the nervous system. Recent discoveries have shed new light onto how this may be occurring, but the process is still not completely understood. Newer studies have also suggested that intestinal bacteria may also be involved in these conditions. This study is being conducted to get a better understanding of how certain types of white blood cells (T cells) and intestinal bacteria may be involved in MS and NMO.
If you have been diagnosed with MS, NMO, or if you are healthy, and you are above the age of 13, you may be eligible to participate in this study. If you are eligible, and if you agree to take part in this research study, we would like to collect a blood sample, and an optional stool sample. By studying these specimens, we hope to learn more about what causes MS and NMO, to expand our knowledge of what happens during the course of these diseases, and hopefully to find better treatments in the future. Participation in the study should take less than two hours.
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