The UCSF MS Research Center is conducting the following experimental studies:
Clinical Trials of Disease Modifying Treatments
Open to enrollment for patients with relapsing multiple sclerosis
CHORD Study - An open-label study to evaluate the efficacy and safety of Ocrelizumab in patients with relapsing remitting multiple sclerosis (MS) who had suboptimal response to other MS treatment
RADIANCE Study - A randomized study to evaluate the efficacy and safety of RPC1063
Vitamin D - RCT Study - A randomized controlled trial of vitamin D in multiple sclerosis
Open to enrollment for patients with progressive multiple sclerosis
NAC Pilot Study - A randomized study to evaluate the efficacy of N-acetyl cysteine on fatigue in patients with progressive multiple sclerosis
Open to enrollment for patients with optic neuritis
ReCOVER - A randomized controlled trial of Clemastine Fumarate as a remyelinating agent in acute optic neuritis
IQooL My MS - Improving Quality of Life in Menopausal women with Multiple Sclerosis
Open to enrollment for MS patients
ORIGINS Study - Discovering the triggers of MS
iMSMS - Microbiome Research in MS
MYO Study - A sub study of TRAC MS
Digital Cognition Study - Brain Re-Training in Multiple Sclerosis
Visual Evoked Poternials (VEP) in the evaluation of Neurological Disease
Neuroimmunology Banking Studies - The collection and banking of samples for studies to understand molecular and cellular immunological mechanisms in MS.
Genetic Susceptibility to Develop MS
Open to enrollment for patients with neuromyelitis optica or neurosarcoidosis
Neuromyelitis Optica - T Cell Recognition of CNS Autoantigens in Multiple Sclerosis and Neuromyelitis Optica
Neuroimmunology Banking Studies - The collection and banking of samples for studies to understand mechanisms of B cell immunology in NMO.
Ongoing studies that are closed to enrollment
OPERA - Study to evaluate the efficacy and safety of Ocrelizumab in comparison to Interferon Beta-1a (Rebif®) in patients with Relapsing Multiple Sclerosis
ORATORIO - Study to evaluate the efficacy and safety of Ocrelizumab in adults with Primary Progressive Multiple Sclerosis.
ReBUILD - A randomized trial to assess an identified molecule as a remyelinating agent in Multiple Sclerosis
PREFERMSStudy - A randomized, open-label study to evaluate the patient retention of Fingolimod.
Sarcoid - Neurological manifestations of Sarcoidosis and ways to distinguish Sarcoidosis from other causes of nervous system Inflammation