A randomized controlled trial of vitamin D in multiple sclerosis
This research is being done to see if giving a high dose of vitamin D to people with multiple sclerosis (MS) makes the disease better. Studies have suggested that people with MS who have lower vitamin D levels have more attacks of MS. It is not known if giving extra vitamin D to people with MS helps make the disease better or not.
Some doctors of people with MS give them vitamin D already, although they don’t know if it is helpful or not. The Institute of Medicine recommends that every person take 600 international units (IU) of vitamin D each day. The study doctors want to know if giving a higher dose of vitamin D, 5,000 IU each day can help lower the risk of MS attacks or MS worsening.
All participants will receive an approved treatment for MS called glatiramer acetate (Copaxone). Half of the people will receive standard-dose vitamin D (600 IU), and half will receive high-dose vitamin D (5,000 IU).
Participation in this study will last for two years.
If you have been diagnosed with a relapsing form of MS, are between the ages of 18-50 and are able to come to UCSF for study visits you may be eligible to participate.